Paraffin-embedding lithography and micro-dissected tissue micro-arrays: tools for biological and pharmacological analysis of ex vivosolid tumors There is an urgent need and strong clinical and pharmaceutical interest in developing assays that allow for the direct testing of therapeutic agents on primary tissues. Current technologies fail to provide the required sample [...]

The chemiluminescence based Ziplex automated workstation focus array reproduces ovarian cancer Affymetrix GeneChip expression profiles Xceed Molecular's Ziplex® system has been tested to evaluate the reproducibility of the signature of gene expression. Dr. Patricia Tonin has applied this new technology to study the pattern of expression of messenger [...]

Using bacteria to deliver drugs Tumours can be dense pockets of tissue that at their core contain very little oxygen. The dense nature of tumours makes it difficult for drugs to be effectively delivered to the central cells. The head of the Experiment Therapeutics axis, Dr. G. Batist, [...]

Open access results lead to advances in acute lymphoblastic leukemia The BCLQ collects samples coming from many types of cancers, including acute lymphoblastic leukemia (ALL). Select ALL samples were analyzed via RNA sequencing by the Leucegene group who went on to published their findings and ensured that their [...]